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5-HTP confirmed to lower Tyrosine stimulation myco

Posted by myco on March 9, 2009, at 16:06:12

In reply to Sustained stimulation with L-Tyrosine + Nardil, posted by myco on March 9, 2009, at 10:30:17

I added a wee bit (~20mg) of 5-htp this morning and it has successfully taken a bite out of the ongoing stimulation from tyrosine.

I think this confirms the inverse relationship between dopamine/norepinephrine and seratonin.

The combination of these two (L-Tyrosine & 5-HTP) in very small doses work well as augments for Nardil, at least in this trial. I think one of the benefits of these two is that they are easily adjustable for a best ratio of effect. I've also been reading that 5-htp should be taken with an aromatic L-amino acid decarboxylase such as EGCG (a catechin in green tea/extract) to prevent seratonin synthesis in the blood (as opposed to the brain).


> Interesting note on L-Tyrosine with Nardil:
> I've been toying with tiny dosages of L-Tyrosine (100-150mg; even these are too high) to augment Nardil (75mg). This stuff appears to build up quite nicely...I imagine with disrespect or ignorance one could wind up in trouble with this stuff on a maoi and not even know it until days down the road. Taken at 100mg twice a day for 3 days straight (that was 4 days ago that I stopped), I am still feeling mild stimulatory effects in my system...some irritability and insomnia goes along with it...actually broke my nice sleep pattern I had going there for awhile. Since we know that tyrosine will deplete seratonin, I will toy next with tiny bits of 5-htp to try to "cancel" out the effect. Logically, I can't see why it wouldnt work since I suspect the NE effect is the ongoing stimulation here.
> Any thoughts?
> myco




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