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Re: Couple studies on inverse relationship of DA + SE

Posted by Alexanderfromdenmark on March 9, 2009, at 9:37:18

In reply to Re: Couple studies on inverse relationship of DA + SE Alexanderfromdenmark, posted by myco on March 8, 2009, at 16:13:21

> No studies indicate long term health risks on any AD on the market as far as I know. I have seen studies (follow ups) after a few years but all they focus on is remission etc. If there is any med class out there that has the potential to be of long term benefit though I would say maois...many people have been on them for many years. Granted they are older than SSRI's so the chances of long term use is more likely (i.e. i've talked to those on nardil for 20 years). But...I dont think I know of anyone who has been on an SSRI (therapeutic dose at least) for years. I know certain people may take lil tiny bits to augment some other type of treatment for many years though. For myself, I have no worries about being on nardil for years. Depression and anxiety has been shown to lead to shorter life anyway...increased risks of disease, such as alzheimers and dementia for example. If i'm gonna lose 10 years at the end of my life I would rather my time be well spent on a med with risks that suffer through it unmedicated and bloody miserable.
> > > Have you tried meds outside the SSRI class? Something like a maoi that plays on seratonin, dopamine, norephinephrine, and GABA (or addition to get this)? Many people need a balance
> > >
> > > > Yeah that's why I think SSRIs often are bad buisness for long-term depression. Less dopamine is bad news for love, motivation, energy, concentration, passion. things lacking in "conventional" depression.
> > > >
> > > > SSRIs have left me flat, unmotivated and apathetic. That is my personal experience though. They work differently for others.
> > >
> > >
> >
> > I'm looking into correcting endoctrine imbalances right now that can cause depression, fatigue and lots of other nasty stuff. If getting my body into balance does not cure my depression, and if CBT and exercise wont, an MAOI will probably be my first choice. Are MAOI's healthy for the brain in the long run though?

What are your benefits and side effects from your own experience with MAOI? How long did it take to work for you? I'm young, so even though depression sucks as much for me, I can still ride it out a bit longer while I'm trying different methods.




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