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Re: MAOI - Is insomnia a good sign of future response? desolationrower

Posted by myco on February 16, 2009, at 19:37:56

In reply to Re: MAOI - Is insomnia a good sign of future response?, posted by desolationrower on February 16, 2009, at 3:35:31

Hi d/r,

If I had a good response to nardil at 45 the 60 then 75 (each a solid 2 week wow what a difference response that slowly faded) then stabilized for weeks on 75 and is now fading again, should I continue to raise or is the constant failure after awhile some other indication? 75 is producing 'apathy' (possibly just lack of sleep though) and a slow increase in anxiety, muscle tension and dep day by day, very subtle though. Seems like I can continue to raise with good efficacy for a limited time, increased sides that get stranger and stranger as I move up, but I'm not sure if its worth it? Looking for a strategy to save this med (get it back to where it was).


> MAO levels vary by level of depression. theres not been much study of proper dosing of MAOIs, just some clinician guesses. insomnia means that if nothing else you at least are taking enough that its affecting monoamine levels. for as much as docs like increasing doses of drug that don't have evidence for benfits of increased dose, or evidence that it doens't help, they sure don't like giving effective dosages of maois.
> -d/r




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