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Re: memantine in lamictal psychosis :( Jeroen

Posted by SLS on February 8, 2009, at 16:27:34

In reply to memantine in lamictal psychosis :(, posted by Jeroen on February 8, 2009, at 6:31:41

> hi, i have a strong feeling memantine can do something good for me, but i have a lamictal induced psychosis for 2 years now
>
>
> i take Abilify 10 mg (AM), Ativan 2.5 mg (PM)
>
>
> i want to ask my doctor for this treatment
>
> Abilify 10 mg, Seroquel 100 mg twice a day upping to 400 mg but scared of tachardia attack, Memantine 5 mg (scared)
>
> can someone tell me if i shoudnt be taking memantine until my dopamine psychosis is resolved. im so scared and sad :(

You are justified in wanting to be careful with memantine. It has been shown to produce psychosis in Parkinson's patients, although I don't know at what rate. Memantine acts as an agonist at postsynaptic D2 receptors (high affinity state) with approximately the same binding affinity as it has for NMDA receptors.


- Scott

 

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