Psycho-Babble Medication | about biological treatments | Framed
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Re: Any ideas?

Posted by bleauberry on November 16, 2008, at 14:59:42

In reply to Any ideas?, posted by antigua3 on November 15, 2008, at 14:45:18

So your Lyrica dose didn't change in terms of how much you take per day, but did change in how much you take per dose. I can see maybe some potential for feeling different from that, but not likely.

But cymbalta, that's a different story. 40mg down to 20mg is huge. If you think about it, going from 20mg to 40mg is a 100% increase. You dropped your dose by that much in one sudden move. Very powerful drug.

Massive prolonged anxiety can follow downward dosage adjustments of ssris or snris. For some reason, the meds with action on norepinephrine, such as cymbalta, seem much more powerful at causing anxiety on discontinuation or dose changing. Messing around with norepinephrine is common and and innocent enough it seems like to the medical world, but in my opinion it is playing in the Major Leagues. Big potential gains, but also more at stake if you lose.

What you are feeling should slowly settle down. It is the body, hormones, and receptors trying to readjust to the new environment. Once they get it figured out, you'll settle into a baseline of some sort. Some people it takes a couple weeks, others a couple months.

To remove any variables that complicate the picture, you might want to return to your previous Lyrica dosing schedule. That way you would at least be able to rule that one out or in as a contributing factor.




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