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Re: Pristiq and Adderall

Posted by West on November 15, 2008, at 15:39:53

In reply to Re: Pristiq and Adderall B2chica, posted by Phillipa on November 14, 2008, at 20:26:45

Think it's mainly SSRI and an NRI in higher doses. Doesn't seem to have a hugely significant DRI effect at prescribed doses and the effect is fixed, meaning more (possibly) 5HT and NE than desired.

Even Bupropion has only a very weak effect on dopamine, despite often being described as an NDRI in a lot of medical literature. A lot of downstream changes make it hard to estimate, although with pristiq at least the metabolism of the drug is more straightforward since it's a metabolite itself. It is not a releaser of DA but amphetamine is.

West

 

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URL: http://www.dr-bob.org/babble/20081114/msgs/863237.html