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Re: Best SSRI for post-steroid HPA axis suppressio

Posted by nuala on September 24, 2008, at 11:14:55

In reply to Re: Best SSRI for post-steroid HPA axis suppression? nuala, posted by Phillipa on September 24, 2008, at 11:05:10

I have some degree of adrenal insufficiency.

I embarked on a course of steroids to correct it.

I had great instability on the multi-dosing and had ups and downs - anxiety, depression, strange thoughts. So, I had to stop.

Now, I am six weeks post hydrocortisone treatment, and am in the midst of a steroid withdrawal syndrome.

My HPA axis is suppressed, my adrenals are suppressed.

The Seroquel I take down-regulatres the HPA axis further and decreases cortisol. Even the 12.5 mg I am on is having a great impact.

A pdoc suggestd elevating the HPA axis by means of an SSRI.

Some SSRIs have this effect. I have read elsewhere in endocrinological articles that using an SSRI such as Lexpro can be helpful.

He reccommened Luvox. I started at 25mg, but it was not a good experience by day 3 - palpiations, extreme over stimulation, etc etc.

I used to be on Lexapro and seemed to tolerate it well. thinking of going back.

Wanted to know if anyone has any suggestions re the types of SSRIs and their effectiveness at elevating the HPA axis and raising cortisol.


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