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Re: Provigil for mental fatigue?

Posted by West on September 10, 2008, at 7:36:15

In reply to Re: Provigil for mental fatigue?, posted by chiron on September 9, 2008, at 21:47:34

I take provigil with cymbalta

Before the provigil the cymbalta had the effect of causing slumps several times during the day. Provigil eliminates the somnolence and stops nausea too.

I have found getting to sleep a little harder, although i should say i have always had problems with sleep. If you're anything like me you can probably expect a little situation-dependent mood brightening and some energy increase: it's listed as a banned substance for athletes and thought to work by inhibiting inhibiting GABA and orexin (a brain chemical which regulates wakefulness, thought to be overabundant in narcoleptics)and enhancing glutamate, although it's exact action has never been publicly defined by manufacturers cephalon. It has a domino effect on various neurotransmitters, is a very weak dose dependent dopamine releaser (in high doses) and increases firing sensitivity at the D2 subreceptor.

Re. aquiring it here, the process was remarkably easy. I simply asked my GP if i could try it to offset the cymbalta. I think its first choice here in the UK for antidepressant induced intrerference of vigilance. All my prescriptions (curently generic zolpidem and brand cymbalta & provigil) are covered by a prepay medical card which costs about 90 a year (about $200). Otherwise each item --in this case 30 x 100mg tablets-- would cost me 6.60 (universal fee per prescription)

Hope that helps





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