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Re: What OCD meds are safe to take with Nardil?

Posted by dcruik518 on August 18, 2008, at 12:47:14

In reply to Re: What OCD meds are safe to take with Nardil?, posted by UGottaHaveHOPE on August 18, 2008, at 2:39:29

The problem with combining MAOIs with re-uptake inhibitors (i.e. either SSRIs or TCAs) is that of serotonin toxicity (serotonin syndrome). This reaction can only occur with antidepressants that posses potency as SRIs. Of the TCAs, this only includes imipramine and clomipramine. The other TCAs are safe to combine with the MAOIs because they do not posses significant SRI potency.




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