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Re: Clozapine not working now what?????

Posted by Quintal on July 8, 2008, at 4:04:50

In reply to Re: Clozapine not working now what????? Jeroen, posted by bleauberry on July 7, 2008, at 19:48:57

I wonder if rimonabant has antipsychotic activity? There could be an overproduction of endo-cannabinoids, or heightened sensitivity of receptors in some psychosis sufferers. I found melatonin to have a mild antipsychotic effect, probably in the same range as 200mg amisulpride (not great, but a noticable improvement).

As with any serious illness, a person has to be willing to work with the treatment and actually want and strive to get better. I've seen people repeatedly sabotage their chances of success, and so long as that continues recovery isn't a likely outcome.

According to my social worker, most people with psychotic disorders have co-comittant personality disorders (mostly antisocial and borderline) which complicate treatment. Psychotherapy and behavioural interventions are necessary for these people because medication alone doesn't usually change the ingrained patterns of interacting with the world and other people that are at the core of PDs.

Q


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poster:Quintal thread:838671
URL: http://www.dr-bob.org/babble/20080706/msgs/838789.html