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Re: Michael: did Buprenorphine work well ? (n/m) Michael Bell

Posted by Marty on May 19, 2008, at 16:54:13

In reply to Re: Michael: did Buprenorphine work well ? (n/m), posted by Michael Bell on May 19, 2008, at 16:41:18

> Buprenorphine did not do much.

Ok. I wonder if it's a placebo effect for people who says it helps. Currently there is nothing CCK related in the pharmas pipeline that I'm aware of...

> 1) Nardil (too many side effects, had near death hypertensive crisis)

Been there, done that. but for the time it worked it was very nice. Btw, the Gabaergic effect has been associated to one of Nardil metabolite that doesn't have any MAOI effect. There's a scientist in Canada who did a couple research on that in the last years. If you're interested I could find the name of the molecule and some pubmed URL about it.

> 2) Klonopin (but induces depression and paranoia)

I wasn't aware paranoia was a possible side-effect of Klonopin. Depression I was; been there, done that.. 2 times. also very irritable.

> 3) Lyrica

I agree that it helps. Even for depression in my case! .. but the 'drunk' feeling isn't a good thing in the long run and some side effects (i.e: Sexual dysfunction) are difficult to deal with. Also it's more addictive than admited.. after 2 years on it I had a hard time stopping it.

Michael, would you give a shot at D-Cycloserine ( + therapy for social phobia) .. ?

btw, what are you on right now ?





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