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Re: Starting Lamictal henryo

Posted by Quintal on April 24, 2008, at 19:14:36

In reply to Re: Starting Lamictal, posted by henryo on April 24, 2008, at 18:36:28

I don't know why you're continuing with this, but yes, I did read my own link and it does say that 10% of patients in the epilepsy trials developed a rash. 10% is 1 in 10. It also says that 14% of bipolar patients developed a rash, making that slightly higher than 1 in 10.

The figure you quoted at the beginning of the article however, only relates to the incidence of *serious rash* associated with hospitalization and discontinuation from Lamictal. This is *not* the overall incidence of benign rash among Lamictal patients - only the most serious ones. The overall incidence of rash is much higher, and these stats are posted further down under 'Dermatological Events'. I'll post them again:
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In epilepsy clinical trials, approximately 10% of all patients exposed to LAMICTAL developed a rash. In the Bipolar Disorder clinical trials, 14% of patients exposed to LAMICTAL developed a rash.
__________________________________________________


Q


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poster:Quintal thread:822705
URL: http://www.dr-bob.org/babble/20080420/msgs/825264.html