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Re: D2 antagonism

Posted by KarenRB53 on March 27, 2008, at 22:14:18

In reply to Re: D2 antagonism yxibow, posted by kieran2585 on March 19, 2008, at 12:51:39

> > > i started aytipical antipsycotics last summer under the guidance of my psyciatrist, she said that it may be my best treatment from the look of my symptoms (apathy, anhedonia) even though ive never heard voices or anything like that
> >
> > They're used for many other things, I know the stigma well of taking one but they're not just used for thatt.
> >
> > , anyway i cant say ive ever noticed much help from them, so im thinking should i really be on these? and can they do more harm than good, and what are the side effects of the d2 antagonism? can it block the activating effects of prozac, NADH and caffeine too?
> >
> > No. In fact low doses of atypicals are used to augment prozac. Caffeine would not be the best if you have any anxiety disorder.
> >
> hi thanks for your post, though after doing some research i found that atypicals would block the activating effects of prozac, i found that geodon is a strong 5ht2c antagonist like prozac and at low doses it is just as activating untill the dose is raised to have enough d2 antagonism on bourd to block the activating effects, so i guess it would be the same with mixing prozac with an AP, i was wondering becouse when i retried prozac under abilify i didnt feel anything and thought it just wasnt going to work for me again, as for caffeine, i know that it shouldnt be used if you have an anxiety disorder, but for me it used to help, which sounds confusing i know
> > What atypical is it?
> >
> im currently on zyprexa but i was on abilify for quite a while
> >
> Generally Zyprexa and Seroquel are considered the safest and the benefits far outweigh the risks, but there are others as well. Somewhere between 0.1 and 0.5% risk of TD probably. Its unclear. Only Risperdal has had any major reports of unwanted effects.
> >
> > -- Jay

Now I'm confused (which isn't hard to do)!! I take Prozac which works great for my depression, however I need to up the dosage but when I do I get hypomanic so I can only take 20mg which doesn't help me as much as I need. I'm trying to find something to use with the Prozac that will allow me to increase dosage of Prozac for the depression but will keep me from becoming hypomanic. Does this make sense?





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