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Re: Trivastal is an a2-adrenoreceptor antagonist? Mishal

Posted by Robert35 on February 1, 2008, at 11:55:25

In reply to Re: Trivastal is an a2-adrenoreceptor antagonist? clipper40, posted by Mishal on November 29, 2007, at 4:24:15

> > I thought that meant that it would cause less norepinephrine to be available in the synapses. However, on Servier's website they talk about the a2-adrenoreceptor antagonist in terms of "restoring central noradrenaline levels to normal". What am I not understanding here?
> The action of Trivastal (piribedil) seems to similar to that old antidepressant Amineptine which acted both on dopamine and noradrenaline. Though I never had any luck in obtaining amineptine, I am taking Trivastal which is also a Servier product. The fast onset of antidepressant action mimics to that of amineptine. If Trivastal is the med for someone, he should not have to wait for all the way to two or more weeks to feel good. Trivastal acts directly to lift anhedonia, amotivation and apathy, three prime symptoms of depression.
> Trivastal is better than wellbutrin. I didn't get any help from wellbutrin when I tried it. Even after two weeks, wellbutrin was the same. But on Trivastal I can feel the difference next day.

Hi Mishal,
I would like to ask you a question about your Trivastal experiment as I am considering it for the reason that I don't seem to tolerate Wellbutrin at all (but somehow have the feeling dopamine + n.e. action is what could help me).
Would you please babble me to ask it privately ?

If you would: thank you (otherwise please disregard this post).
Best regards,





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