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Re: beta carbolines to reverse benzo cognitive pro linkadge

Posted by Quintal on August 9, 2007, at 21:18:51

In reply to Re: beta carbolines to reverse benzo cognitive pro, posted by linkadge on August 9, 2007, at 9:00:13

>People have the right to deny it exists, because it honestly may not.

Look at the title you chose for this thread.

>Yes, but just because it is natural doesn't mean it can't have bad side effects of its own.

6,3'-dinitroflavone isn't natural, it's a synthetic compound derived from a natural flavonoid.

>I had a hell of a withdrawl from valerian. Valerian withdrawl can actually cause cardiac failure. While I prefer chamomile, I can get depressed if I drink too much, and I also have withdrawl if I stop it abruptly.

If this is true, then it bodes badly for you with the much stronger synthetic benzodiazepine receptor agonists. It's illogical that the small amounts of low-bioavailability benzodiazepine-like compounds found in valerian and chamomile tea would produce stronger withdrawal effects than than larger doses of the more potent synthetic benzodiazepines. I know you didn't say that, but it stands to reason that someone who suffers such strong reactions to Valerian and chamomile would fare much worse with Klonopin and Valium under the same circumstances. Perhaps it's a blessing that your doctor, as the guidelines recommend, has restricted you to short courses of low-dose benzos so far. If you'd been taking them for years at high doses I feel sure your experiences would have been different.

>For instance, a person who is high in estrogen, which desensitizes GABA-A, may have much less effect of a standard dose of valium than somebody who has high progesterone (sensitizes GABA-A).

How is this relevant? I'm not intimidated.

>Well, seing as they are not approved for inducing amnesia......

Lorazepam is indicated for peri-operative amnesia in the UK. I don't have any US drug references to hand but I know lorazepam is certainly used, and recommended, as a pre-medication to induce amnesia during medical procedures in the US though, regardless of whether it is licensed for this purpose.

>The highest concentration of benzodiazapine receptors is in the amydala. For a person who's cognition is hampered by an overactive amydala, who knows how the cognition might actually improve when the amydala is tamed down. Its just like how Dilantin is used as a nootropic. For some people, it apparently improves cognition

Same again. None of this changes the fact that therapeutic doses of benzos cause significant amnesia and cognitive impairment.





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