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Re: A Thought On ENSAM Phillipa

Posted by Glydin on August 8, 2007, at 6:40:28

In reply to A Thought On ENSAM, posted by Phillipa on August 7, 2007, at 23:48:04

> If EMSAM does not go through you're digestive tract yes I know it does the liver. But not the stomach so does this mean it's the first nonfattening ad every made?

~~~ I'm thinking based on it being topically absorbed as opposed to GI absorption, probably is not going to effect drug properties when it comes to metabolism, appetite, satiety... etc. The difference is HOW it gets into the body, not what it's doing once it gets there. All the fat versus not stuff is a complex interplay with fair amount of that interplay's input guided in the brain.

In theory, the fact that perhaps lower dosing can be used (as the skin can be a good absorber for some meds) may have it's advantage as negative effects, in theory, may be diminished. That said, I still hold to the idea the brain is located at the top of the body for a reason. (Smile)


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