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What can you combine with SSRI's?

Posted by jealibeanz on March 29, 2007, at 4:58:04

To prevent weight gain? I would consider trying again if I could reduce the possibility of this side effect that seems inevitable with me.

I don't mean combine w/ Wellbutrin or Topamax. Wellbutrin caused lots of weight gain for me, and I think the only reason Topamax works for some is that it controls appetite. I don't need appetite control, since I wasn't overeating on AD's.

I'm thinking there's a few other "tricks" that have been explored. I just can't quite recall what they may be. I know there are a few drugs like Glucophage or Byetta that diabetics use to control blood sugar. That might help if SSRI's are somehow messing with my insulin output and blood sugar levels (I've seen that proposed somewhere.)

It would help to know why exactly they cause weight gain with me (and others like me). There's definitely a metabolic change. It's very clear with me... anything drug that manipulates serontonin even the slightest bit causes my fat cells to search for anything to make them grow! (i.e. Wellbutrin = small serontonin reuptake + big weight gain; Straterra = no serotonin reuptake + no weight gain).

Does this all mean that these "selective" reuptake inhibitors aren't really so selective, rather, they have systems effects as well as CNS?

Any ideas? Haha, not that I think I'd ever get prescribed something that isn't common, but whatever, just wondering.




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