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Re: wait a second? linkadge

Posted by Squiggles on November 6, 2006, at 7:05:43

In reply to Re: wait a second?, posted by linkadge on November 5, 2006, at 21:15:13

> Believe it or not, there is a lot of controversy about the neuroprotective/neurotoxic actions of lithium.
>

There is no controversy at all. It is well
known that lithium is toxic over a certain dose.
Like some drugs, it has a narrow therapeutic index; that is , it does not take much deviation in dose range to become toxic. Warfarin is like that for example, and many other drugs.


> Lithium has proconvulsant and anticonvulsant effects. Lithium can be *highly neurotoxic* if it goes over the upper blood level.

Doh!
>
> Also, when lithium is combined with the cholinergic agent pilocarpine, it can induce a model of temporal lobe epilepsy.

Now why would i want to combine it with a drug
for xerostomia induced by cancer? I don't have that condition.

>
> http://www.cogsci.ecs.soton.ac.uk/cgi/psyc/newpsy?7.32
>
>
> Linkadge
>
>

Linkadge, this post is exactly the kind of post that I was asking for an information editor on for this group. I understand that Dr. Bob cannot hire the entire staff of the American Psychiatric Association to help out, but i would say you are coming close to fear-mongering.

Nobody likes the side effects of psychiatric drugs. I have said this over and over on the board -- we need better drugs. But this message is not what I need anyway. You may as well tell someone on chemotherapy that the reason he is so sick is because of the chemotherapy -- yeah he knows that. But he takes it for a reason.

Squiggles


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Psycho-Babble Medication | Framed

poster:Squiggles thread:699922
URL: http://www.dr-bob.org/babble/20061104/msgs/700848.html