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Re: Weight Gain doesn't happen for everyone

Posted by Another Phil on October 1, 2006, at 23:33:19

In reply to Re: Weight Gain doesn't happen for everyone, posted by Racer on September 5, 2006, at 17:55:40

> The weight gain seems to start about 4 months in on the drugs, and it can be mitigated using other drugs. Topomax is one drug being used A LOT these days to counter the weight gain, and sometimes metformin, which has more adverse effects and is much less commonly tried.

Several years ago, I gained about 15 lbs. while on 5 mg/day of Zyprexa. There was no losing that weight--eating lots of salads, running a lot, working out regularly. So, I stopped the Zyprexa and the entire 15 lbs. came off in about 6 weeks.

Soon after, I started on Zyprexa again, but this time taking 1000 mg of Metformin twice a day. I was on this combination for over two years with no weight gain. I'll admit, though, that having to take a medication that helps the body use insulin more efficiently makes me wary of the mechanism by which Zyprexa causes the weight gain in the first place--especially with a history of diabetes in my family. Damn, I need to get off of Zyprexa.





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