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Re: Emsam insomnia

Posted by Jost on September 26, 2006, at 19:26:44

In reply to Re: Can't Take it AnyMore !!!!!!!!, posted by Declan on September 26, 2006, at 17:44:08

Insomnia is a problem with Emsam, no question.

First, there's accommodation over time-- perhaps not total, but substantial in reducing insomnia.

Even more, taking the patch off for some part of the night may be a crucal element of successful use for some people (myself included).

I'd also like to emphasize that Scott is, IMO, correct about adherence to the dietary restrictions on higher emsam doses, esp. if the patch isn't removed at night. If absorption stays within expected levels, the dietary restrctions may not be necessary even on stronger patches.

So far, however, the effect of non-standard conditions. such as heat, even during transportation, or individual differences in absorption have not been studied adequately. Therefore, some danger of reaching a level where tyramine could be problematic remains--esp. since it's not tyramine at one meal, but over days, that can be implicated.

Until these issues are further investigated some degree of dietary caution should be practiced.





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