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Re: how strong is buspar's D2 antagonism? iforgotmypassword

Posted by linkadge on September 25, 2006, at 15:34:49

In reply to Re: how strong is buspar's D2 antagonism? linkadge, posted by iforgotmypassword on September 25, 2006, at 13:29:27

I was under the impression that it was a postsynaptic d2 receptor antagonist. I didn't know of any affinity for presynaptic receptors.

It has a short half life, so at moderate doses I wound't be too concerned about permamant movement problems.

You could always try it with a dopamine agonist to counteract that side effect.

I always thought that buspar + mirapex would be very interesting. Combined dopamine + serotonin agonism.

Certain herbs like skullcap combine 5-ht1a agonism and d1 agonism.





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