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Re: Interesting MAOI's info JaclinHyde

Posted by Caedmon on May 20, 2006, at 13:12:11

In reply to Interesting MAOI's info, posted by JaclinHyde on May 20, 2006, at 11:30:52

> "Both the irreversible MAOIs and the RIMAs rarely cause cardiac effects and at therapeutic doses have little effect on seizure threshold. Hepatotoxicity (e.g., progressive, necrotizing, hepatocellular damage) has occurred in some patients receiving MAOIs of the hydrazine type (e.g., phenelzine/Nardil) making it advisable to check liver function periodically in patients receiving high doses and in those receiving prolonged therapy with these drugs. Risk of hepatotoxicity with the non-hydrazine MAOIs (e.g., tranylcypromine/Parnate, pargyline, selegiline) and the RIMAs (e.g., moclobemide, brofaromine) is absent or minimal."

Interesting! BTW, do you happen to know the source? (It was a quotation after all.)

- Chris




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