Psycho-Babble Medication | about biological treatments | Framed
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Re: lithium increases tyrosine hydroxylase

Posted by Caedmon on April 6, 2006, at 18:43:51

In reply to lithium increases tyrosine hydroxylase linkadge, posted by Squiggles on April 2, 2006, at 18:45:10

> Stahl makes an interesting point that "overall,
> lithium is effective in only 40 to 50% of patients"; i find that incredible but he may not
> be defining his sample very well.

That's what I was wondering. 40-50% of *which* patients?

In unipolar depression: I understand, from my pdoc, that even though Li is the most studied drug for antidepressant augmentation, it tends to produce only marginal response in most patients. (It and T3. This might just be his clinical experience, I don't know. Such a statement surprised me, but then, I haven't read very deeply into the literature. Remission v. response are different things - most studies only look at response.)

- C




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