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Re: Nardil dosing times to reduce insomnia?

Posted by SLS on February 13, 2006, at 23:16:05

In reply to Nardil dosing times to reduce insomnia?, posted by DavidLA on February 13, 2006, at 20:48:36

> When do you take Nardil?
> I take it all (45 mg) in the morning and I still often have insomnia at night. I've tried to switch to taking it in the evenings, but it was very difficult and I went back to taking it the morning. I'm wondering if anyone has figured out a dosing regiment that reduces their insomnia.
> Thanks,

I doubt the insomnia is dependent upon dosing schedule. Unlike Parnate, which has a short half-life and amphetamine-like properties, Nardil produces a more consistent blood level. It hangs around all day long. The insomnia is probably due to the inhibition of MAO rather than a direct stimulant effect of the Nardil or its metabolites. For this reason, it really wouldn't matter what time you took it once monoamine oxidase inhibition is established.

You may have little choice but to add a hypnotic drug to help you sleep.

Nardil + sleep deprivation makes a powerful combination for someone who is bipolar. It very often induces mania.

- Scott




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