Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Haloperidol (Haldol)

Posted by med_empowered on July 30, 2005, at 7:12:46

In reply to Re: Haloperidol (Haldol), posted by Declan on July 30, 2005, at 4:29:23

yeah...i get really upset when i read about the continued use of higher-range doses of haloperidol and other "old-school" neuroleptics. Apparently, one of the big problems with the older neuroleptics--and one reason why the "atypicals" seemed so attractive, especially when they were first introduced--is that doctors (particularly in the UK and the US, it seems) had/have a tendency to be really heavy-handed with them. Thus, it seems that haloperidol given @ 4mgs/ a day *MAX* (most people can take less--I read a study where 2mgs got good results) can give pretty good control of positive symptoms and a bit of help with some negative symptoms. However, as ed_uk pointed out, there was/is a tendency to sometimes RX haldol well into the double-digits...10,15, part of *standard* treatment; I shudder to think what dosages the "treatment resistant" were given. Thus, today, when Thorazine is used you often see RXs for a 300mgs or so for acute mania/acute schizophrenic psychosis...20, 30 years ago, it wasn't entirely uncommon to see 700mgs, sometimes dosages exceeding 1,500mgs RX'd. Also, its kind of scary to realize that for a long time, neuroleptics were "discovered" when the investigational compound showed signs of *neurotoxicity* (especially Parkinson's-like symptoms and reduced motor activity) in animals...the old-school antipsychotics were identified not through a specific effect on psychosis, but through their neurotoxic effects on test animals. Now that's crazy.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:med_empowered thread:535356