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Re: Effexor, Snapping and Smoking

Posted by jessers11581 on April 21, 2005, at 16:52:56

In reply to Effexor, Snapping and Smoking, posted by robinyyz on April 21, 2005, at 15:13:32

> Hi all...I have been on 75mgs of Effexor XL on and off for over a year. I find the medication helps but I have some strange side effects. First of all, when I'm on the medication, I seem to snap, yell and generally get angry with people for the stupidest reasons. Also, I get urges to smoke, when normally I don't. Anyone else get these side effects?

I feel similarly on Cymbalta (you can read my post above for more details). Wellbutrin also did this to me when I tried to use it in the past, only it was ten times worse! I'm pretty sure it has something to do with increasing norepinephrine and dopamine. If either of these get too high, they can lead to aggressivness. I spoke with my pshychiatrist about it several minutes ago, and she confirmed that this is true. She suggested for me to decrease my Cymbalta dose for a while. SSRI's are the least likely (in my experience) to cause irritability. They work only on serotonin, which promotes a calm, peaceful feeling. The only drawback is that it can make you TOO calm, and then you don't get anything accomplished. Oh, the joys of anti-depressants!

P.S. Smoking can actually boost serotonin levels in your brain, so feeling more addicted to cigarrettes probably means that you're low in serotonin. I know that this is the case with me, and I've been smoking like a chimney lately! I hope this helps!




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