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Re: can Cymbalta be mixed with Wellbutrin?

Posted by med_empowered on April 20, 2005, at 19:52:19

In reply to can Cymbalta be mixed with Wellbutrin?, posted by jessers11581 on April 20, 2005, at 17:55:59

hey! The Wellbutrin-Cymbalta thing **might** work, but try to stick to the old rule: "start low, go slow" when doing potentially tricky drug combos. My new shrink considers cymbalta the equivalent of throwing a potent SSRI, like say zoloft, and a potent SNRI, such as Straterra, into one colorful capsule. Apparently, some research indicates that your average dose of Cymbalta is stronger on both the serotonin and the neuroepinephrine ends than your average dose of Effexor. Keep in mind though that Cymbalta (and effexor, and the TCAs...) raises blood-pressure, at least at the 60mgs/day dose; the average is 4pts, I think, but some people are hypersensitive and have to stop taking it. Wellbutrin also tends to raise blood pressure...keep in mind that Wellbutrin is chemically related to Tenuate, a stimulant diet-drug that was pretty popular in the '70s. So, expect stimulant-like effects; increased anxiety, over-stimulation, racing heartbeat, etc. are possible, along with the benefits, which may be considerable. If you try this, I'd seriously recommend doing some work on your anxiety first or while you introduce wellbutrin.




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