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Re: Low dose doxepin or trimipramine w/ selegiline? KaraS

Posted by zeugma on January 29, 2005, at 17:04:52

In reply to Re: Low dose doxepin or trimipramine w/ selegiline? zeugma, posted by KaraS on January 29, 2005, at 16:07:57

One last question, trimipramine's D2 receptor antagonism would be a good thing for me, wouldn't it? (esp. if I'm taking an SSRI?)

Well, if your theory of super-sensitive D2 autoreceptors is true, then yes, it would be a good thing. Trimipramine is a curious drug. its known pharmacological profile resembles that of clozapine, the prototype of the atypical antipsychotics, and yet it seems to be better as an antidepressant than an antipsychotic.





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