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Re: Low dose doxepin or trimipramine w/ selegiline? zeugma

Posted by KaraS on January 29, 2005, at 16:07:57

In reply to Re: Low dose doxepin or trimipramine w/ selegiline? KaraS, posted by zeugma on January 29, 2005, at 10:37:03

> trimipramine is not metabolized to imipramine. But it might induce tachycardia because it is antimuscarinic. It's similar to doxepin, except it has virtually no effect on NE or 5-HT, and resembles an atypical antipsychotic in some ways, including D2 receptor antagonism.
>
> -z


Thanks. I'll soon see if I can tolerate the doxepin still. If not, I probably couldn't take trimipramine either (at least not without a beta blocker).

One last question, trimipramine's D2 receptor antagonism would be a good thing for me, wouldn't it? (esp. if I'm taking an SSRI?)


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poster:KaraS thread:449038
URL: http://www.dr-bob.org/babble/20050128/msgs/449804.html