Psycho-Babble Medication | about biological treatments | Framed
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Re: SSRI Theory

Posted by jboud24 on October 15, 2004, at 11:36:29

In reply to Re: SSRI Theory, posted by AJsmommy on October 15, 2004, at 8:38:06

Thanks for all the responses.

I am aware of the involvement of second messenger systems as well in the brain. But I didn't realize that the pre-synaptic neurons could still synth 5-HT. Duh. I should of thought of that.

I also think that the dual SRI/NRI's are going to show more success than the SSRI's will due to the involvement of the norepinephrine in anhedonia, lack of drive/interest, and so on. Now if they would just make a version of Cymbalta with a longer half-life I might jump at that, but 12 hours seems like asking for trouble in regard to missing a dose and experiencing discontinuation.

I see my pdoc on the 28th of this month, where I am going to bring up the possibility of Nardil or Parnate. My therapist, who is also a psychopharmacologist agrees that this would probably be a good route to explore.

Decisions, decisions.





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