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Re: tricyclic and benzodiazepine interaction Squiggles

Posted by Sad Panda on July 18, 2004, at 11:37:33

In reply to tricyclic and benzodiazepine interaction, posted by Squiggles on July 17, 2004, at 8:32:28

> Hello again,
> Has anyone experienced the following results
> from mixing clonazepam with imipramine?
> - rapid weight loss
> - lassitude, apathy, lack of libido, anorexia
> - fatigue
> - feeling and being cold even in very hot weather
> - diarrhea
> - and last but not least, blessed ability to sleep
> which was the reason for adding clonazepam to anxiety provoking imipramine;
> If these symptoms are normal, then it's worth
> the combo. But I am a bit worried if these
> are symptoms of something more serious - hopefully
> a CBT will tell.
> Also, is clonazepam combined with imipramine, more likely to induce these symptoms, than say another benzo?
> Thanks for reading, and looking forward to
> any feedback from your experiences.
> Squiggles

Hi Squiggles,

They are unusual symptoms, how long have you been taking these two? I would get a liver test. Apathy, lack of libido & fatigue could be side effects of Imipramine, but rapid weight loss certainly isn't. With Imipramine & a benzo combined, you are more likely to be constipated, gain weight, be hot & sweaty. If anxiety is your main problem, you would probably be better off with Amitriptyline or Clomipramine instead.





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