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Re: Chronic pain -best med and weird reactions ravenstorm

Posted by BarbaraCat on July 16, 2004, at 19:29:59

In reply to Re: Chronic pain -best med and weird reactions, posted by ravenstorm on July 16, 2004, at 16:29:57

This is very interesting because I was having a very similar discussion with m/husband yesterday who has recently stopped smoking. The class he went to said that nicotine acts primarily on dopamine but there's a very close tie between dopamine and endorphins as far as pleasure seeking and reward is concerned. The lines are a little blurred with the question, is it pleasure enhancement or pain relief? Narcotics act on dopamine as well as the opiod system.

Since dopamine is in the same pathway as NE, and if there's some correlation with dopamine and endorphins, then sounds logical. - BarbaraCat

> When I was on paxil I had muscle pain and worsened headaches which I didn't reallize were from the SSRI until I got off of it.
> I'm a massage therapist and based on client information (I see a lot of people with chronic pain) it seems to be the norep. not the serotonin that helps with pain. I have clients who have gained relief from Wellbutrin, nortriptyline, desipramine and effexor. Non of the SSRIs on there own have helped with pain relief. Again, totally anecdotal.




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