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Re: wash-out before maoi

Posted by King Vultan on May 20, 2004, at 7:43:53

In reply to wash-out before maoi, posted by fuji on May 19, 2004, at 18:15:54

> Anyone know what a typical wash out period would be from ssri to maoi? I am about 5 days off of efexr but my doc wants me to be 5 (yes, she said 5) weeks off of prozac & 2 weeks off efxr. That means five unmedicated weeks for the first time in about 13 years. Pretty freakin' scary in my book!

Yes, unfortunately, five weeks is a prudent washout period for Prozac because of its ridiculously long half life. If I were in your place, I would be apprehensive about waiting any less time than that. I do understand your concerns about being unmedicated for that length of time, as I also had to go through a washout period when switching to an MAOI (and then another period when the dosage I was taking was insufficient), but perhaps there will be enough residual effects on receptor densities from the drugs you've been taking to aid you in the transition.





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