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Re: Amisulpride- 5 and a half weeks...need advice now! ace

Posted by rod on January 8, 2004, at 5:28:43

In reply to Amisulpride- 5 and a half weeks...need advice now!, posted by ace on January 7, 2004, at 18:52:57

This might hurt, but I have to tell you what comes into my mind ;)
I agree with scott-d-o. I dont think it works for you. Did you change the dosage of Nardil? The last information I could remember was 105mg. Right? Did you increase it since you started Amisulpride? Didnt you take it at a lower dose, before you started Amisulpride? Ok, I admit I am too lazy to look it up ;)
In general, I doubt a dopaminergic agent works for OCD. Arent they contraindicated for OCD in general? But you said you have a somewhat atypical OCD, whatever this means. BTW could you describe your OCD a little better? Any rituals?
If you look at pubmed, many abstracts state ocd and ad(h)d are inverse neurochemic situations. Amisulpride activates for example the forebrain (it increases attention and concentration for me), while in calssic OCD it is already overstimlated (hyerglutamiergic state of the forebrain in OCD). And most serotonergic agents seem to correct this state of overactivity. BTW, did you try any other SSRI besides Zoloft (Sertraline)?? Didnt you take this one? My personal opinion about Sertraline is that is not the best drug to treat OCD. What about Luvox, Celexa, Lexapro? I know, you once tried Anafranil which resulted in what you described as serotonin synndrome. Too short period between switching nardil and anafranil? I dont know. I dont want to influence you since you seem to do great with Nardil. Im just curious





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