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Re: GH3, DMT - natural MAO Inhibitors?

Posted by Caleb462 on April 4, 2003, at 18:47:41

In reply to GH3, DMT - natural MAO Inhibitors?, posted by Verne on April 4, 2003, at 12:35:06

> I have atypical depression (along with BPD and PTSD) and have tried everything but MAO's. I'm concerned about the risks and was wondering whether there are any natural legal substances that have MAO inhibitors in them?
> My searches have brought up a couple possibilities - GH3 (prozaine?) and DMT. They too seem to pose some risks. I can't figure out whether they are herb derivitives or synthetic drugs. Brainquicken out of Canada came up too but they don't list the ingredients.
> Anyone know of any others or have any suggestions?
> Verne

DMT is a naturally-occuring tryptamine, meaning it is in the same family of chemicals as serotonin, melatonin and psycolibin. It is a psychoactive drug, and is used for it's strong psychedellic/hallucinogenic effects. It is definitely NOT an MAOI however.

The confusion probably arose because plants that contain DMT are often ingested along with plants that contain the natural MAOIs harmine, harmaline and tetrahydroharmine. DMT is not active orally unless an MAOI is present as well. Also, DMT is illegal.

So, as far natural MAOIs... there are the harmala alkaloids previously mentioned. They are contained in plants such as Syrian Rue, Yage and Passionflower.

The Yohimbe plant is a mild MAOI.

St. John's Wort is said to have VERY slight MAOI properties as well.

That's all I know of. You should note, though, that just because something is natural - doesn't mean it has no risks. The harmala alkaloids carry the same risks with them as synthetic MAOIs.




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