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Re: Great links-Thanks gentlemen.. Big Question drdaviss

Posted by JESSsMom on January 12, 2003, at 19:41:43

In reply to Re: Great links-Thanks gentlemen.. Big Question JESSsMom, posted by drdaviss on January 9, 2003, at 16:01:19

> JM asked the following:
> > If you go to the link Peter provided, click on Wellbutrin and scroll down to April 2001 where it says "drug interactions with paxil/prozac/effexor (generic names are provided).........
> > Am I reading this correctly--?--Wellbutrin reduces the effect of Effexor but not Prozac or Paxil's efficacy?
>
> The article describes the effect of adding Wellbutrin to someone already on Paxil or Prozac or Effexor. It says that the blood levels of Effexor went up (potentially *increasing* both its effectiveness and its side effects), but the Paxil and Prozac were unchanged. It doesn't say how much it went up, and I don't have the article handy. It also said the Effexor metabolite (o-desmethylvenlafaxine) level went down, meaning the Wellbutrin probably slowed down Effexor's breakdown, making it last longer.
> =Steven Daviss MD
> http://www.psychopharmINFO.com

Thank you so much for explaining that to me. I just caught your post tonight, it wasn't under the original thread. Thank you again.
JM


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