Psycho-Babble Medication | about biological treatments | Framed
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Re: SSRI-induced dopamine depletion

Posted by oracle on November 29, 2002, at 0:05:56

In reply to Re: SSRI-induced dopamine depletion, posted by Larry Hoover on November 28, 2002, at 18:11:01

> Dopamine depletion in the prefrontal cortex is associated with remission of depression. You just can't generalize. One of the problems with drugs to control neurotransmitters is that they affect all cells with a certain receptor type the same way, even though you might want some to increase activity and others to be reduced.
> Even though dopaminergic activity or total dopamine might fall during antidepressant therapy, there's no way to say whether that's good or not. Nobody knows what it means.

I put it another way, once you start talking about depletion in the context of causing mental illness you are way off, and have missed the complexity of these systems and are ignoring how much we do not know.

Or to put it another way, if it was depletion that caused mental illness, they would of been cured decades ago.




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