Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: P.S. Selegiline and the Pill jackstraw232

Posted by Rick on October 18, 2002, at 20:02:35

In reply to Re: P.S. Selegiline and the Pill, posted by jackstraw232 on October 18, 2002, at 14:19:28

Jackstraw, it's hardly an "assertion", it's a well-recognized aspect of the drug's pharmacology. It is documented in the manufacturer's official monograph. BTW, if you search on the terms selegiline and methamphetamine in Medline, you'll come up with about 120 abstracts. It's sometimes thought the amphetamines, even though in fairly small amounts, may contribute to selegiline's activating and potentially anxiogenic effects.

Here's a passage from the selegiline monograph at
http://www.rxlist.com/cgi/generic/seleg_cp.htm :


Effects resulting from selegiline administration may also be mediated through its metabolites. Two of its three principal metabolites, amphetamine and methamphetamine, have pharmacological actions of their own. they interfere with neuronal uptake and enhance release of several neurotransmitters (e.g., norepinephrine, dopamine, serotonin). However, the extent to which these metabolites contribute to the effects of selegiline are unknown.

Rick

> By the way Rick, what evidence do you have for your assertion that one of selegiline's metabolites is methamphetamine? It is awkward that you chose not to cite any evidence for your claim. Please follow up.


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Rick thread:108414
URL: http://www.dr-bob.org/babble/20021012/msgs/124185.html