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Re: How much WB? Anyuser

Posted by Ritch on September 22, 2002, at 14:06:05

In reply to How much WB? Ritch, posted by Anyuser on September 22, 2002, at 11:51:11

> How much WB did you add to your 10mg Celexa? Do you take it every day, or as needed to counter s/e?
>
> Do you think you are especially sensitive to SSRIs, or do you think that the manufacturers prescribe too much drug? Hard question to answer, I suppose. My pdoc thinks all AD manufacturers prescribe in too-high amounts.
>
> Thanks for your help.

Hi,

I am med-sensitive to nearly all AD's, due to being bipolar. I am especially sensitive to SSRI's for some reason, but they do help with anxiety/mood a lot (which is good and sometimes bad). I think the doses are way too high for many folks like me because they are developed for trials for unipolar depressives and they are targeting efficacy as a monotherapy (just my guess here). Also, maintenance doses of AD's can be much lower and stave off relapse in a lot of folks. That's what I need-I just want a med regime that is low-dose that I can just take all the time and just forget about it-but that's easier said than done.

AD-wise, I switched from Celexa(+buproprion) to Effexor(+bupropion) about two-three months ago. The main reason was I get little or no nocturnal reflux from Effexor as opposed to Celexa (and Prozac, etc.). Let's see, when I was in the middle of wintertime BPII depression, I was taking 2.5-5mg of Celexa + 75-150mg bupropion. The bupropion wasn't added to counter s/e from the Celexa, I just don't respond to a serotonergic AD well during my BPii depressions, I need a stim-like med for it to clear up. When I am in a part of the year when my moods are mixed or generally hypo that much AD (either Celexa or bupropion) would have me climbing the walls.

Mitch


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