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Citalopram pharmacology - Mitch

Posted by dr. dave on August 20, 2002, at 5:21:03

In reply to Re: Lexapro is different Patson, posted by pharmrep on August 20, 2002, at 0:06:06

'Celexa' 20mg is 10mg s-isomer and 10 mg r-isomer. The r-isomer is effectively inert as an SSRI or anything else. Celexa only works because of the 10mg s-isomer in it. 'Lexapro' is the 10mg s-isomer on its own. It's pretty hard and expensive to produce separately, and it's a funny thing to do when the r-isomer has virtually no pharmacological action at all.

Lexapro 10mg is Celexa 20mg with 10 mg of an inert substance expensively removed.




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