Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Lamictal, update Squiggles

Posted by Maximus on August 2, 2002, at 23:03:52

In reply to Re: Lamictal, update Maximus, posted by Squiggles on August 2, 2002, at 21:42:58

> Interesting - i wonder what the advantage
> of this augmentation is over the old
> just lithium dose with Rivotril and/or some
> other benzo.

Well, actually i can not speak for myself yet. "Fingers crossed". However, my pdoc went at so much conferences and contributed at many studies (in that direction), than i tend to believe her.

Grosso modo, here's why:

1- Lithium is "probably" the best anti-manic/hypomanic agent. Lithium is a very well known med. But the Lithium is also "so and so" (generally) for the depression. And Li does almost nothing for the "rapid cyclers". So many many bipolars need an antidepressant for their depression. Not a big deal.

2- Lamictal is without a doubt the best agent (anticonvulsant) for the bipolar depression. More and more studies tend to prove it. The side effect profile is indeed very low. Lamictal is also marvelous for the rapid cycling condition. But its anti-manic properties are weaker than Lithium.

3- There is absolutely no interaction between Lithium and Lamictal. In combo, we need a lower dose of each other. Moreover, in combo the need for a benzo is almost nil.

Their mechanism of action is extremely complicated. But the most important is their action on glutamate receptors via also their own mechanism.

But as you know, in psychiatry, there is no panacea and of course no "one fit for all".

Hope that helps!


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Maximus thread:115003
URL: http://www.dr-bob.org/babble/20020731/msgs/115012.html