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Re: Any new info on Gepirone or Pagoclone

Posted by lansolut on June 5, 2002, at 8:00:42

In reply to Re: Any new info on Gepirone or Pagoclone Elizabeth, posted by JohnX2 on March 1, 2002, at 5:34:51

I don't know when it will be approved but I'm in a Phase III study (the extended release version) and it's a very good drug. It lifts depression and, to a lesser degree, anxiety. There are vitually no side effects other than some very minor ones at startup - which go away after a few days.

The only problem with it (and this could just be me) is that when it wears off in the evening, the anxiety comes back. Can't take more at night because it can cause insomnia.

> I'll be waiting in the Pagoclone line with my wallet open.
> Hopefully I'll be off my Klonopin addiction by then.
> Why do I suck so much at these habit forming medicines?
> -John
> > > I have read lots on Gepirone and Pagoclone. Interested in any new information on these two drugs. Mostly whether or not they are close to being approved.
> >
> > I don't know about that, but if you're interested in trying gepirone, you might consider high-dose Buspar. They're very similar drugs, and Buspar acts as an antidepressant in high doses (around 45-90 mg). (It's quite safe; Buspar was originally studied as an antipsychotic, and although it was completely ineffective, doses over 1 g were well tolerated.)
> >
> > Pagoclone looks interesting, but I have a hard time coming up with a justification for taking an expensive name-brand drug when I could get a generic benzodiazepine much more cheaply.
> >
> > -elizabeth




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