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Re: Anyone still on Imipramine (Tofranil)sp?

Posted by Lia Mason on May 5, 2002, at 23:02:35

In reply to Anyone still on Imipramine (Tofranil)sp?, posted by jay on May 3, 2002, at 20:26:14


I'm so glad you posted. I'm trying imipramine and I can't find too many people to give me feedback.

I'm at 150 and it took a long time to get here. I started at 10 mg and increased 10 per week. I think it's helping me but I'm also on Sam-e and Lamictal so it's hard to say. I was prescribed imipramine for a chronic pain condition and it's worked great for that. I'm hoping to use imipramine as my primary antidepressant because I don't like the sexual side effects of the SSRI's and MAO's.

I have all the typical side effects but they're not debilitating. I get a little lightheaded if I stand up too fast. I'm a bit constipated and have some dry mouth. I have not gained weigbht, though. I had what felt like increased heart beat when I first took it but that went away. I'm generally tired and I don't know if that's depression or drugs. My doctor says that if it's imipramine it will wear off.

For the record, I was on Nortriptyline before this and couldn't tolerate it. I found it very fatiguing and the lightheadedness was much worse.

My doctor said that imipramine's therapeutic dose ranges anywhere from 150-300.

Good luck and please keep posting your experience. I'm very hopeful about imipramine. I've been on literally everything else and couldn't live with the side effects. I know people on this board are often down on tricyclics because they're side effect ridden ("dirty"). But I'd rather have a lot of minor side effects that I can live with than one major one that I can't.





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