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Re: Is Reboxetine worth the wait?

Posted by OldSchool on March 31, 2002, at 10:37:35

In reply to Re: Is Reboxetine worth the wait? OldSchool, posted by Bob on March 31, 2002, at 0:25:37

>
> > You wont ever see Reboxetine marketed in the USA. Forget about it...dont expend any mental energy thinking about it. As far as meds already available that work mostly on NE like Reboxetine, there is desipramine a tricyclic. Also, high dosage Effexor is similar to Reboxetine.
> >
> >
> > Old School
>
> Why do you say this, Old School? I thought that Reboxetine was grinding its way through the FDA?
>
> Bob


Well first of all, I totally admit I do not know for sure. Im giving my opinion, which is a calculated guestimation of sorts, based upon things Ive read. I turned down a chance to get into a reboxetine clinical trial at Duke University back in late 1998. The person running the trial told me rebox worked pretty good for young people, but not so much for older folks. Why I have no idea. It was a closed trial so there was a good chance I wouldnt get reboxetine that Id get placebo instead. So I didnt waste my time. If it had been an open trial, I probably would have gone for it.

Anyway, Reboxetine was up for FDA review a year or two ago and everybody was excited about it. Then it got shot down...rejected. The rumor going around was that Eli Lilly was trying to get some similar NE selective AD on the market and there was politics involved, so Reboxetine got blocked. However, this was just the rumor and I have no real idea why reboxetine wasnt FDA approved a while back.

Its been hashed and rehashed in the USA for years now and I seriously doubt we will ever see Reboxetine in the USA. I really dont. But I could be wrong, but I wouldnt hold your horses over this one.

Desipramine is the closest thing to Reboxetine we have in the USA. Try desipramine...its basically the same thing just more side effects like anti-cholinergic side effects.


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