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Re: stimulant and antidepressant combination-Ritch

Posted by Bekka H. on March 29, 2002, at 0:49:11

In reply to Re: stimulant and antidepressant combination-Ritch Bekka H., posted by Ritch on March 28, 2002, at 23:56:55

Hi Mitch,

So, you cut the Celexa into eight tiny pieces or does it come in a liquid form? I tried cutting it with a pill cutter, but I usually ended up with crumbs.

You've probably told me this already, but could you remind me what other meds you're on?

The anxiety reaction you described from Celexa plus Dex is similar to the rxn. I got from every other SSRI plus stimulant combo. Celexa + Dex was the only such combo that didn't give me a terrible reaction. I didn't do well on Celexa + Dex, but at least I didn't end up in the ER. I'm convinced I've had mild serotonin syndrome on a number of occasions from the other ssri+stim combos. For me, Celexa + Dex seemed to negate eachtother. Whatever is good about each one individually seems to be counteracted by the other. Celexa and other ssris are supposed to lower dopamine levels, and amphetamines can deplete serotonin and dopamine, so over the long haul, it just doesn't work for me -- unfortunately. Whenever I've been off of Celexa for a long time (at least 4-5 months or so) and then I resume it at very low dose plus Dex, I feel excellent for about 10 days to two weeks, and then I poop out. I've also found that Celexa makes me have to increase the Dex dose just to counteract the Celexa-induced fatigue, etc., so I end up developing tolerance to Dex much faster. Then I end up having to stop Dex for several months just to lose the tolerance. As you can see, this is a most unsatisfactory combination for me, but someone else might do very well on it. I have a tough time on nearly all med combinations.





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