Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: tools to offset Serzone cognitive issues?

Posted by JohnX2 on February 19, 2002, at 16:55:52

In reply to Re: tools to offset Serzone cognitive issues? Ritch, posted by Mr. Scott on February 18, 2002, at 23:09:28

> How about trazodone + Nortryptaline? create your own serzonelike creation with two other meds.

This is an interesting combination.
Trazodone is a more potent alpha-1 antagonist.
Are you going after the urinary retention?

This doesn't sound like a bad combo if I can
keep the anti-muscarinic side effects from
killing me.

A little more research into histamine-1 blockade
indicates that it faciliates the release of
serotonin. Does this imply that allergies can
diminish serotonin release? Anyways one of
Trazodones metabolites is something called mCPP.
This is a direct agonist of the serotonin receptor.
So basically all bets are off as to what the
presynaptic receptor is doing. Then the medicine
blocks the postsypantic 5ht-2 receptor. Maybe
all this gets around a foobar histamine system.
Interesting. If I could get Serzone or Trazodone
to work I would be home free.


> By the way I've heard amitrptyline and Nortryptaline (it's metabolite) are the best TCA's for pain. I heard that this is because they affect membranes like tegretol, but I'm basically relaying theory here.
> Scott




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:JohnX2 thread:94516