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Re: tools to offset Serzone cognitive issues? Ritch

Posted by JohnX2 on February 19, 2002, at 12:18:03

In reply to Re: tools to offset Serzone cognitive issues?, posted by Ritch on February 18, 2002, at 21:35:10

I'm confused about the nortriptyline idea?

The pain I am experienced is not neuropathic
per se. i.e it is not tingling in my extremities.
Unless i don't understand the definition of
neuropathic pain. The pain I experience is a
REALLY bad pressure build up in my head. I'm
starting to think this may be histamine related
as strong anti-histamine doses aleviate it.
I've taken every anti-depressant beside tricyclics
and also every anti-convulsants. 4 things fix
this pain: Klonopin, Topamax, Serzone, and very
strong doses of anti-histamines. This problem
became severe the same year I started to develop
bad allergies in Austin, so I'm thinking my
explosion of mood issues may be related. Just
my latest thought. Also the chronic head pain can change
dramatically as I travel across the country.

Its not totally obvious why Serzone works, it
just does. Are you guys suggesting a possible add-on of
Nortriptyline to Serzone to offset the cognitive
decline? I've thought about taking TCAs just to
see if their anti-histamine properties would help
fix my problem anyways.

Thanks for any feedback.


> > >
> > > I may be starting Serzone again as it is
> > > the only medicine besides Topamax that alleviates
> > > really bad tension headaches and I am having
> > > an impossible time tapering off this last 1 mg
> > > of Klonopin.
> > >
> > > Funny, I found Topomax alleviated
> > > my myofacial pain that Klonopin seemed to be
> > > doing and swiftly weened Klonopin from 6 mg to
> > > 2 mg, but from 1 mg downward the headaches have
> > > been unbearable.
> > >
> > > So I'm thinking of maybe restarting Serzone.
> > > It totally eliminated these headaches before, and
> > > I may be able to take it if only for a short while
> > > to chip off this last mg of Klonopin. The major
> > > issue is that Serzone caused in the past very
> > > bad cognitive dysfunction and it was a bit scary
> > > to operate my car.
> > >
> > > So my question is if people have tried augmenting
> > > serzone with other meds to help with cognitive
> > > side effects? Any other ADs or stims?
> > >
> > > Thanks for any feedback.
> > >
> > > -John
> >
> > John,
> >
> > Have you thought about going a 'low-dose' Serzone? That was the only way I could take it.
> >
> > I also find the tricyclic (the brand name only, strange as it is) for Nortriptyline in the 25mg or so range helps with cognitive performance. I found the stims made me feel 'dumb' at times, mostly because they made me so anxious, I couldn't think straight.
> >
> > Good luck,
> >
> > Jay
> John, What do you think about just adding Nortripytline instead of Serzone? I didn't get any *confusion* with it, and it even helped focus better than Wellbutrin. And, since it is a TCA-you shouldn't get worsened neuropathic pain. Just a guess. If the NT dose is low-enough you might be "out of the threshold" enough not to worry about hypomania-but possibly "in there" for analgesia and improved focus.
> Just another idea,
> Mitch




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