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Re: tools to offset Serzone cognitive issues? jay

Posted by JohnX2 on February 19, 2002, at 2:22:09

In reply to Re: tools to offset Serzone cognitive issues? JohnX2, posted by jay on February 18, 2002, at 17:35:12

Thanks for the suggestions.
I've really been curious about a TCA.
This is strange....
I get a PROFOUND anti-depressant/mood stablization
effect when I take a nice dose of the
anti-histamine chlorpheniramine maleate. I mean
it totally wipes out most of my problems.
I just don't understand and am starting to believe
that part of my problems may be allergies.

Anyways, I looked into these anti-histamines and
found that they are strongly linked into NMDA
transmission. So the TCA's also have some anti-histamine
like properties which might make them a good candidate
for me.

At 25 mg, what is Nortriptyline like? Do you sense
anti-histamine like side effects?

Thanks for taking the trouble to give feedback.

> >
> > I may be starting Serzone again as it is
> > the only medicine besides Topamax that alleviates
> > really bad tension headaches and I am having
> > an impossible time tapering off this last 1 mg
> > of Klonopin.
> >
> > Funny, I found Topomax alleviated
> > my myofacial pain that Klonopin seemed to be
> > doing and swiftly weened Klonopin from 6 mg to
> > 2 mg, but from 1 mg downward the headaches have
> > been unbearable.
> >
> > So I'm thinking of maybe restarting Serzone.
> > It totally eliminated these headaches before, and
> > I may be able to take it if only for a short while
> > to chip off this last mg of Klonopin. The major
> > issue is that Serzone caused in the past very
> > bad cognitive dysfunction and it was a bit scary
> > to operate my car.
> >
> > So my question is if people have tried augmenting
> > serzone with other meds to help with cognitive
> > side effects? Any other ADs or stims?
> >
> > Thanks for any feedback.
> >
> > -John
> John,
> Have you thought about going a 'low-dose' Serzone? That was the only way I could take it.
> I also find the tricyclic (the brand name only, strange as it is) for Nortriptyline in the 25mg or so range helps with cognitive performance. I found the stims made me feel 'dumb' at times, mostly because they made me so anxious, I couldn't think straight.
> Good luck,
> Jay




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