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Re: got a zanaflex prescription; wish me luck

Posted by JohnX2 on November 30, 2001, at 18:07:17

In reply to Re: got a zanaflex prescription; wish me luck JohnX2, posted by Elizabeth on November 30, 2001, at 15:52:57

Hi Elizabeth/Janejj,

I've seen many references to Clonodine (Catapres)
being used for benzo withdrawl. I think this is
fairly common. I haven't seen much about Zanaflex.
Zanaflex has a crummy 1/2 life (time in your body)
so if it works I may need to take many doses
in one day. There is a sustained release version
in Europe which I would try to attempt to talk
my doctor into if this helps. Another med that
I have seen references to treat benzo withdrawl
is Baclofen. I have also had success with Neurontin.
It also seems that nmda antagonists like memantine
share similar properties. So there are many classes
of meds: alpha-2 agonists, anti-convulsants, gabaergic
meds, nmda antagonists. All are helpful for similar
pain syndromes. I think they all have utility in
psychiatry too. I believe some of these atypical
meds I have been studying like Zanaflex and memantine
could be novel adjuncts for people with treatment
resistant depression associated especially with
a response that "poops out".

Anyways, it is believed that alpha-2 agonists
may be helpful in depression/anxiety associated with
post-traumatic stress disorder. I think this
is where I qualify. So I always seem to come
to this conclusion that the meds that are best
suited to treat my pain are indirectly the correct
ones to treat my mood disorders. funny.

Regards and thanks for the support.
"I'll keep you posted".


> Good luck with this! I'll be interested to hear how it works for you. I've never heard of clonidine or other alpha2-adrenergic agonists being used for benzo withdrawal but maybe it will help. (Are you sure it's a partial agonist, BTW?)
> -elizabeth




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