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Re: lamical with ssri?

Posted by jazzdog on November 2, 2001, at 17:32:33

In reply to Re: lamical with ssri? jazzdog, posted by Cam W. on November 2, 2001, at 13:26:40

> Jazzdog - I'd be interested in seeing SSRI-Lamictal study. It does makes sense that this combination will be tried clinically, anyway.
> Thanks Jazzdog - Cam

Cam - I'm sorry I don't have any studies to refer you to. My psychiatrist emailed the depersonalization unit at Maudsley to find out if anything had been helpful with derealization. They emailed back and said they'd had about 50% success with a combination of about 250 mg lamictal and an ssri. I don't know how large their sample was. This gave me hope, because I've also read - here and elsewhere - that lamictal can be useful for atypical depression, which I also suffer from. I'm a lifelong eat-and-sleep depressive who burst out gloriously about fifteen years ago in a prolonged psychotic mania - most fun I've ever had!

While we're on the subject of lamictal, my shrink was speculating on what its mechanism of operation might be. I've read a couple of people on the depersonalization board talk about lamictal working for them by 'more clearly defining and separating the sleeping state and the waking state.' Any theories? JohnX2, feel free to jump in.

Thanks - Jane




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